Let's know about DNA TOPOLOGY it's structure, functions and more.
It's overview and structure[part-1]
Are you aware about the behavior of "DNA TOPOLOGY". Have you any idea if you want to know about DNA TOPOLOGY then you have good in Mathematics because this you cannot understand well it. Let's know about DNA TOPOLOGY. Topology is an esortic field of mathematics. It is conceptly difficult subject to teach students because it requires students to visualise three dimensional that are not easy to portray using two dimensional slides or chalkboard. DNA TOPOLOGY can be described in Mathematical terms, and a number of outstanding articles address this aspect of the subject (5,17-19). While mathematics provides important foundation for understanding DNA TOPOLOGY. In order to fully understand dna topology, students familiarizes themselves with three keys Mathematical concepts:twist (tw), writhe(wr), and linking numbers (nk) [5,17-20].Twist represent the total number of double helical turns in a given DNA segment. By convention, a right- handed twist of waston and crick structure is assigned a positive value.Writhe is a property of spatial course of DNA and is defined as the number of times of double helix crosses itself if the molecules is
Protected in two dimension. The helix-helix crossover (i.e., nodes) are assigned a positive or negative values based on the orientation (i. e., handness) of the dna axis. The numerical term that describes the sum of the twist and writhe is called linking numbers, which represents the total number of dna molecules. Mathematically, these properties of DNA can be expressed
as:
Lk=tw+wr
Two critical points need to be emphasized. First, the ends of the dna is fixed in a space, lk is invariant value that cannot be changed without opening the systems (i. e.,breaking the dna chain). Second in absences of the knots or tangles, tw and wr are (at least mathematically) fluids value that can be interconverted. The classical example for this interconvention is a telephone cord [5,17-20]. In its "native" unstretched configuration the cord is coil(I. e.,writhes about itself). But there is no visible twisting of cord. If the cord is stretched then all of coiling is lost and the cord is visibly twisted.
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